Cellular immune responses in red blood cell alloimmunization
نویسندگان
چکیده
منابع مشابه
Responder individuality in red blood cell alloimmunization.
Many different factors influence the propensity of transfusion recipients and pregnant women to form red blood cell alloantibodies (RBCA). RBCA may cause hemolytic transfusion reactions, hemolytic disease of the fetus and newborn and may be a complication in transplantation medicine. Antigenic differences between responder and foreign erythrocytes may lead to such an immune answer, in part with...
متن کاملRed Blood Cell Alloimmunization in Patients with Thalassemia Major and Intermediate in Southwest Iran
Background: Transfusion is the mainstay treatment of patients with thalassemia major and occasionally in thalassemia intermediate. Alloimmunization is an unwanted side effect of blood transfusion. The present study intended to determine the frequency of alloimmunization in patients with β- thalassemia major and thalassemia intermediate in Southwest Iran. Patients and Methods: This was a cross-...
متن کاملFrequency and Risk Factors of Red Blood Cell Alloimmunization in Thalassemia Major Patients in Markazi province
Background: Thalassemia is one of the most common genetic disorders throughout the world. Blood transfusion plays an important role in the treatment of thalassemia but it leads to numerous complications such as iron overload and alloimmunization. This study evaluated the frequency and risk factors associated with alloimmunization in thalassemia major patients living in Markazi province, Iran. ...
متن کاملRed-blood-cell alloimmunization and number of red-blood-cell transfusions.
BACKGROUND Patients receiving red-blood-cells may form antibodies against the alloantigens expressed by red-blood-cells, with the risk of serious morbidity and the need for extensive phenotype-matching in subsequent transfusions. The incidence of alloimmunization is considered variable for specific patient groups and for first time antibody formation. We therefore studied the cumulative inciden...
متن کاملBenefits of Delayed Cord Clamping in Red Blood Cell Alloimmunization.
BACKGROUND AND OBJECTIVE Several studies have shown the benefits of delayed cord clamping (DCC) in preterm and in healthy newborns at short and long term. Our objective was to evaluate the potentials benefits and risks of DCC in red cell alloimmunization. METHODS This was a comparative before/after study of all living born neonates followed after fetal anemia requiring in utero transfusion. D...
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ژورنال
عنوان ژورنال: Hematology
سال: 2016
ISSN: 1520-4391,1520-4383
DOI: 10.1182/asheducation-2016.1.452